Momwe kudya Kwambiri Kumasinthira Ubongo

Kodi mukudabwa ngati cheesecake yamasana ano isintha thupi lanu? Ngakhale ambiri a ife timaganiza kuti zikusintha m'chiuno, ndi ochepa omwe amakayikira ngati amasinthanso ubongo. Koma zimatero, ndipo kafukufuku yemwe wangotulutsidwa kumene (Rossi, 2019) akutiwonetsa momwe tingachitire izi.

Lingaliro lakuti ubongo umakhudza pafupifupi chilichonse chimene timachita siliyenera kudabwitsa; omwe timakonda, momwe timamvera, komanso zomwe timadya zimakhudzidwa ndimachitidwe aubongo. Kunama mkati mwenimweni mwa ubongo wathu mumakhala gulu la maselo omwe amakhala ndi hypothalamus. Hypothalamus imayang'anira zochitika zingapo zokhudzana ndi kupulumuka kwamitunduyo; mikhalidwe yomwe, monga ndimawuzira ophunzira anga nthawi zambiri, imakhala ndi ma F anayi amalamulo a hypothalamic - kumenya, kuthawa, kudyetsa, ndi kukwatira.

Monga madera ambiri aubongo, hypothalamus imagawika m'magawo ang'onoang'ono; awa amatchulidwa kawirikawiri pogwiritsa ntchito mawu omwe amalozera kulunjika. Mwachitsanzo, taganizirani za hypothalamus yotsatira. Dzinalo limatanthauza kuti limakhala m'mbali mwa hypothalamus, kapena kutali pakati. Omwe tili ndi chidwi ndi zizolowezi zomwe timachita tikudziwa kuti kuti muphunzire momwe ubongo ungakudyetseni mosakayikira mudzawoloka ndi lateral hypothalamus. Izi ndichifukwa choti kapangidwe kake ndikofunikira pakuthandizira kapena kuwonjezera kudya. Imachita izi pochepetsa kagayidwe kake, chimbudzi, kutsekemera kwa insulin, ndi kumva kukoma, kutchulapo zinthu zochepa. The lateral hypothalamus imasamalidwanso kwambiri pamitundu yonse motero imakhala yoyenera kutengera mbali zosiyanasiyana zamadyedwe amunthu. Chifukwa chake mukaganiza kuchuluka kudya, ganizirani zochulukirapo mu hypothalamus yanu yotsatira.

Ubalewu udawonetsedwa koyamba m'maphunziro oyambira omwe sanali anthu, omwe adawonetsa kuti makoswe omwe amawononga hypothalamus yawo yam'mbali nthawi zambiri amakana kudya ndipo, m'malo mwake, monga munthu angaganizire, kuyambitsa kapena kuyambitsa dera lino zimalimbikitsa kudya kosakhutira. Zoyipa zakulumikizana pakati pa kudya ndi hyperalalamus yotsatira zakhala zikuwerengedwa mozama ndipo izi sizingatheke pazokambirana zathu. Dziwani kuti, asayansi ambiri amakhalidwe abwino adapereka maola ochulukirapo kuti atidziwitse kumvetsetsa kwathu komwe hypothalamus lateral imathandizira pakudya ndi chakudya. Nkhani yolembedwa ndi Rossi ndi anzawo amachita izi, powonetsa momwe kudya kwambiri kumakhudzira hypothalamus yotsatira ndi momwe zosinthazi zimakhudzira momwe timadyera.

Mwa kuphatikiza njira zosiyanasiyana zamagetsi, oyesererawo adasanthula ngati kudya kwamafuta ambiri kwasintha mawonekedwe amtundu wa cell mu lateral hypothalamus. Kuyesaku kunapangidwa kuti kufananize mawonekedwe amtundu wama mbewa omwe amalandira zakudya zamafuta ambiri motsutsana ndi omwe amalandila zakudya zabwinobwino. Adapeza kusintha kwa majini chifukwa chonenepa kwambiri m'maselo osiyanasiyana amkati mwa hypothalamus. Komabe, kusintha kwamphamvu kwambiri komwe kumapangitsa kuti munthu akhale wonenepa kwambiri kunachitika m'maselo okhala ndi puloteni yotchedwa vesicular glutamate transporter mtundu-2. Nthawi zambiri, maselowa amagwiritsa ntchito mankhwala othamangitsa ubongo otchedwa glutamate. Anasanthula ma cellwa ndikupeza kuti amalabadira kumwa shuga; komabe, kukula kwa kuyankha kumadalira momwe nyama ingalimbikitsire: Kuchuluka kwa chakudya chomwe nyamayo imafuna kumakhudza momwe ma cell amayankhira shuga.

Kudyetseratu mbewa (zosalimbikitsa) kapena kuyambitsa kusala kwa ola la 24 (dziko lolimbikitsana) asanayese kuyeserera kolimbikitsa chakudya. Maselo osangalatsa a hyperalalamus of lateral of the world in the low motual state (osakhala ndi njala) adakumana ndi kutseguka kwakukulu atamwa shuga kuposa nyama zomwe zinali kusala kudya. Izi zikuwonetsa kuti kukhutira ndi chakudya kumakhudza mphotho yakubwezera chakudya chomwe chimachitika mkati mwa hypothalamus yotsatira.

Chomwe chinali chosangalatsa kwambiri pakulemba kwa ma cell osangalatsazi ndikuti zakudya zamafuta ambiri zidasinthanso mayankho awo. Momwemonso, maselo azinyama zomwe amadya pafupipafupi amakhalabe ndi mwayi wodziwa momwe shuga amagwiritsidwira ntchito, koma mbewa zama mbewa zomwe zimadya mafuta ambiri zimayamba kuchepa shuga; motero, kusintha kwa ubongo.

Zotsatirazi ndizatsopano komanso zosangalatsa, chifukwa zimawonetsa kuti chakudya chamafuta ambiri chimasinthitsa kusungira mphotho ya chakudya m'maselo am'thupi la lateral hypothalamus. Kuphatikiza apo, tsopano tikuwona kuti chakudya chopatsa mafuta chambiri chimasinthira hypothalamus yotsatira mwa kulepheretsa kuyankha kwawo kwa neural ndikufooketsa "kusweka" kwamkati pakudya. Mwanjira ina, zakudya zamafuta ambiri zimatha kusintha ubongo wanu kuti uzilimbikitsa kudya mopitirira muyeso.